Sanjeev Sabhlok's blog

Thoughts on economics and liberty

What is the likelihood of a coronavirus (SARS-CoV-2) vaccine? And of coronavirus treatments?

Placeholder post. I’m reading/ hearing a lot of contradictory views about corona vaccine/ treatment, so will try to find the answer:

BIG PICTURE FACTS

“2019-nCoV (now called SARS-CoV-2) is the seventh member of the family of coronaviruses that infect humans, after MERS-nCoV and SARSnCoV” [Source].

AT PRESENT NONE OF THESE SEVEN ARE EITHER PREVENTABLE OR CURABLE:

  • “No vaccine or antiviral is available for human coronavirus infections” [Source]
  • “There are no specific antiviral medications approved for this disease. Symptoms are managed with supportive care.” [Source]

MY CURRENT SUMMARY ASSESSMENT

As I read more, I’ll update this assessment:

Although nothing is available today to prevent or treat coronavirus, there is a reasonable chance (not certainty) that (a) a treatment will be found before we get a vaccine; and (b) that at least one of these (vaccine or treatment) will be found in the next 12 months.

It is a good idea to not get the virus if one is above the age of 50. Preventative actions in the next 12 months could pay off in the future.

Prospect of vaccine

“a coronavirus vaccine is still months — and most likely years — away.” [Source]

“several research groups have reported the development of broad-spectrum and pan-coronavirus treatment and vaccine strategies, including those effective against both SARS-CoV and MERS-CoV.” [Source, 2017]

“In the light of a dwindling interest in SARS research in the last 5 years, MERS research has contributed to advancing the development of pan-coronavirus therapeutic options that are also effectively against SARS-CoV.” [Source, 2017]

Prospect of treatment options

LOPINAVIR

An HIV protease inhibitor, lopinavir is being studied along with ritonavir for the treatment of MERS and SARS coronaviruses. The repurposed drug is already approved for the treatment of HIV infection under the trade name Kaletra [Source]

FAVILAVIR

“The National Medical Products Administration of China has approved the use of Favilavir, an anti-viral drug, as a treatment for coronavirus. The drug has reportedly shown efficacy in treating the disease with minimal side effects in a clinical trial involving 70 patients. The clinical trial is being conducted in Shenzhen, Guangdong province.” [Source]

REMDESIVIR

“Bruce Aylward, an assistant director-general of the World Health Organization (WHO), has stated “there is only one drug right now that we think may have real efficacy and that’s remdesivir.” It was reported on 25 February 2020 that clinical trials for this drug were in progress, with results possibly available within weeks” [Source]

BUT NOTE

An ebola drug developed by Gilead Sciences that was found to be ineffective is now being tested in phase III randomised clinical trial in partnership with China.

The trials are being performed on 761 patients in a randomised, placebo-controlled, double-blind study at multiple hospitals in Wuhan, the epicentre of the novel coronavirus outbreak. The results from the trials are expected to be available over the next few weeks.

According to a report by The New England Journal of Medicine (NEJM), remdesivir, when administered to a coronavirus patient in the US, appeared to have improved the clinical condition. [Source]

 

“Passive immunotherapy involving the administration of mAbs is a promising antiviral treatment and prophylactic strategy, as evident from ZMapp and palivizumab which can effectively prevent Ebola and respiratory syncytial virus infections in humans respectively” [Source, 2017]

SPECIFIC DETAILS ABOUT INDIVIDUAL CORONAVIRUSES

SARS

Towards a safe and efficient SARS-coronavirus vaccine

Middle East respiratory syndrome coronavirus (MERS-CoV)

MERS-CoV is a member of the subfamily Coronavirinae, genus Betacoronavirus, subgroup lineage 2c. Analysis of human MERS-CoV sequences has identified several circulating genotypes. These distinct genotypes are phylogenetically classified into clades A, B, and, most recently, C, which correlate with outbreaks of MERS among humans [Source]

MERS-CoV remains incapable of sustained human-to-human transmission [Source]

Vaccine for Mers coronavirus ‘looks promising’

REFERENCES

 

Coronavirus treatment: Vaccines/drugs in the pipeline for Covid-19

2019 Novel coronavirus: where we are and what we know – Cheng and Shan, 7 February 2020

WIKIPEDIA PAGES

2019–20 coronavirus outbreak

Coronavirus

Betacoronavirus

BACKGROUND: TYPES OF CORONAVIRUS

Although SARS-CoV and MERS-CoV are both classified under the order nidovirales and family coronaviridae, they are phylogenetically distinct, with SARS-CoV belonging to lineage B and MERS-CoV belonging to lineage C of the betacoronavirus genus. [Source, 2017]

 

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Some recent notes on Dayanand Saraswati’s belligerent and bigoted Hinduism

For my record and reference – based on recent study. Of course, there are many other references to Dayanand on this blog over the years.

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Dayanand Saraswati's "enlightened" caste system with two types of schools. – from Satyarth Prakash

Posted by Sanjeev Sabhlok on Saturday, 15 February 2020

Further details of how the "qualitative" (not hereditary) caste system should operate – Dayanand Saraswati's Satyarth Prakash

Posted by Sanjeev Sabhlok on Saturday, 15 February 2020

Dayanand Saraswati was smitten by the need to differentiate people. His theory was that these are not hereditary, but…

Posted by Sanjeev Sabhlok on Saturday, 15 February 2020

Dayanand Saraswati is crazy delusional when he says such things. Vivekananda at least recognised that "qualitative"…

Posted by Sanjeev Sabhlok on Saturday, 15 February 2020

It is amusing to read Dayanand's arguments that caste is real, but qualitative: "Since the divine formlessness and…

Posted by Sanjeev Sabhlok on Saturday, 15 February 2020

Here Dayanand Saraswati provides a mechanism to allocate "caste", but ALSO TO TAKE AWAY ONE'S CHILDREN!! Ghastly! Reminds me of Plato's Republic.Who in his right mind thinks up such rubbish?

Posted by Sanjeev Sabhlok on Saturday, 15 February 2020

Dayanand fully supports Manusmriti. He has a really sad message for "Sudras" – you guys are supposed to serve the higher…

Posted by Sanjeev Sabhlok on Saturday, 15 February 2020

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Sadguru’s wisdom – extracted by Rocky Karthik. Rocky rocks!

This is from rationalist Narendra Nayak’s FB post. – apparently the material was compiled by one Rocky Karthik (I’d love to meet Rocky!)

This is interesting – noting here for future reference:

===EXTRACT===  

Here is a list of his knowledge, not up to date because after that we have his gyan on vaccines, CAA etc.
Jaggi’s Irrational and UnScientific Claims Compiled by Rocky Karthik:
1. Water Has Memory:
A chemist asked this question about how can water have a memory, do you have any scientific evidence to support that claim.
To that Mr. Jagadish Vasudev explained about Butha Suddhi, Butha Siddhi, how to succeed in life etc but never answered the original question.. (I observed 1 min of silence for his blind followers.)
Supporting Video: https://youtu.be/6C1p4HUHlfE
2. Rudraksh purifies Aura around a person: 
He says wearing a rudraksh helps in purifying the aura around us.
Aura is paranormal term. It doesn’t exist for real. There is no scientific evidence for its existence, and only psychic and mystic people claim to have seen it around people. They even say they can predict the size of it.
Supporting Video: (at 2:15)
3. Darwin stole Evolution from Hindu Mythology:
In this video he claims that Darwin made us all monkeys by stealing the theory of evolution from ancient Indian scriptures. He gave example of Dasavataras which are symbolic way of describing how humans evolved.
Supporting Video:
4. His Wife Announced Her Death 9 months before:
In this video he claims that his wife announced 9 months ahead of time that she is going to die and she did it.
Also he claims that woman wear a metal ring to their feet just to make sure they don’t accidentally leave their body when they get to a certain state of exuberance. Similarly his wife removed all the jewelers before she went into Mahasamadhi (which is another paranormal term like Aura)
Whereas her father lodged a police complaint suspecting that he killed her.
Supporting Video:
5. Sani Temple is built based on planet Saturn:
He says this planet influences certain human beings life’s in a certain way.
6. Universe is formed when Shiva roared and spat out galaxies:
He said this openly in NDTV during a debate with India’s famous scientists. He says this is mentioned in Yogic Sciences which were written 15000 years. (Lol 15000 years ago I don’t think there was a language at all)
Supporting Video (at 43’)
7. Sleeping to the North harms health:
In this video he says sleeping to north is bad and it causes harm to human health.
But US Geological Survey website says there is no significant effect of earth magnetic field on humans.
It’s website says:
“Does the Earth’s magnetic field affect human health?
Not directly. High-altitude pilots and astronauts can experience higher levels of radiation during magnetic storms, but the hazard is due to the radiation, not the magnetic field itself. Direct effects on human health from the magnetic field at the Earth’s surface are insignificant. Geomagnetism can impact the electrically-based technology that we rely on, but it does not impact people themselves.”
8. Death in old age makes you take rebirth within 48 hours:
In this video, director Shekar Kapur asks Vasudev about Reincarnation (at 7:25), then Vasudev answers “if you die an accidental death then chances of finding another womb are very little because you carry a different level of intensity so you cannot find a womb. Unless you are at a right level of intensity you are not suitable to take on an other body. So if you died of old age, energies became feeble and you are at the right level of intensity. You went to bed and you never woke up. Such a person may get back into another womb within 48hrs”.
At 3:38: he says death is a change of clothes.
Supporting Video:
9. Last but the most hilarious:
He says Egyptian Pyramids and Tenples were built by Indians.
Supporting Video:
10. He is saying yoga/inner engineering cures diabetes. No medical doctor will approve of this claim.
Supporting Video:
11. Telepathy is real and it can work by tuning the mind in a certain way.
Supporting Video:
12. Mercury solidifies at room temperature in presence of lord Shiva.
Supporting Video:
This man did a chemical experiment to explain how to solidify mercury at room temperature. And proved there’s no miracle in Sadhguru and other mystic’s claims.
13. Food turns into poison during eclipse.
Supporting Video:
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